Crosslinking, Labeling and Protein Modification
TARGETMOL CHEMICALS INC CL-C6-PEG4-O-CH2COOH 50MG
Also available in 5 mg 10 mg 100 mg and bulk. Please contact Fisher for quotes. Cl-C6-PEG4-O-CH2COOH (PROTAC Linker 4) is an effective pegylated PROTAC linker which is often used in PROTAC synthesis of chloroanes (HaloPROTACs). purity: 99%
![Medchemexpress LLC 4,7,10,13-tetraoxahexadecanediamide, N1,N16-bis[3-(11,12-didehydrodibenz[b,f]azocin-5(6H)-yl)-3-oxopropyl] | 2182601-68-7 | 97.4% | 810.93 | C48H50N4O8 | 25 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000204012.png-250.jpg)
Medchemexpress LLC 4,7,10,13-tetraoxahexadecanediamide, N1,N16-bis[3-(11,12-didehydrodibenz[b,f]azocin-5(6H)-yl)-3-oxopropyl] | 2182601-68-7 | 97.4% | 810.93 | C48H50N4O8 | 25 MG
DBCO-PEG4-DBCO is a PEG-based bifunctional dibenzocyclooctyne (DBCO) linker that enables strain-promoted alkyne-azide cycloaddition (SPAAC) for copper-free click chemistry. It contains two DBCO groups connected by a PEG4 spacer, is supplied as a white-to-yellow solid, and is used as a cleavable linker in ADC and PROTAC synthesis.
- enables copper-free SPAAC (strain-promoted alkyne-azide cycloaddition)
- contains two DBCO reactive groups connected by a PEG4 spacer
- high purity: 97.4% (HPLC)
- molecular weight: 810.93 g/mol
- supplied as a white-to-yellow solid with recommended sealed, moisture-free storage
Broadpharm Azido-PEG5-Val-Cit-PAB-OH, 500 mg, 98% purity, Cleavable linker, Enzymatic cleavage with Val-Cit, Azide reactive group
Azido-PEG5-Val-Cit-PAB-OH, 500 mg, 98% purity, Cleavable linker, Enzymatic cleavage with Val-Cit, Azide reactive group
Medchemexpress LLC DBCO-PEG6-NHS ester | 95.0% | 737.79 g·mol⁻¹ | C38H47N3O12 | 10 MG
DBCO-PEG6-NHS ester is a bifunctional click-chemistry reagent combining a dibenzocyclooctyne (DBCO) moiety and an N-hydroxysuccinimide (NHS) ester separated by a six-unit polyethylene glycol spacer. It is designed for amine-specific conjugation and copper-free strain-promoted alkyne-azide cycloaddition (SPAAC) with azide-functionalized partners, and is supplied as a light yellow liquid.
- Bifunctional linker with DBCO and NHS ester groups.
- PEG6 spacer improves solubility and reduces steric hindrance.
- Reacts with primary amines for stable covalent attachment.
- Performs copper-free SPAAC with azide groups for bioorthogonal labeling.
- Purity approximately 95% as provided in product documentation.
- Store protected from light and under inert atmosphere; recommended low-temperature storage for long-term stability.
Medchemexpress LLC Dspe-peg-fitc | 1000788-53-3 | >=95.0% | 100 MG
DSPE-PEG-FITC (average MW 10,000) is a fluorescein-labeled PEGylated phospholipid that functions as a fluorescent lipid probe for incorporation into liposomes, micelles, and other lipid-based nanocarriers. Its amphiphilic structure allows integration into lipid bilayers to enable optical labeling, tracking, and imaging of nanoparticles in vitro and in vivo.
- Fluorescent label FITC for visualization and tracking.
- Average molecular weight 10,000 Da.
- Amphiphilic structure integrates into lipid bilayers.
- Suitable for liposome, micelle, and nanoparticle formulation.
- Available in multiple package sizes for experimental flexibility.
Medchemexpress LLC Bromoacetamido-PEG5-azide | 1415800-37-1 | 95.5% | C14H27BrN4O6 | 10MG
Bromoacetamido-PEG5-azide is a heterobifunctional PEG-based linker used for PROTAC assembly and bioconjugation. It combines a bromoacetamido electrophile, which undergoes nucleophilic substitution with thiols and other nucleophiles, with an azide group that participates in copper-catalyzed azide-alkyne cycloaddition (CuAAC) and strain-promoted azide-alkyne cycloaddition (SPAAC). The PEG5 spacer imparts flexibility and improved solubility, and the material is supplied at approximately 95.5% purity for research applications.
- Heterobifunctional design enables sequential orthogonal reactions.
- Bromoacetamido group reacts selectively with nucleophiles, such as thiols.
- Azide moiety compatible with CuAAC and SPAAC click chemistries.
- PEG5 spacer enhances solubility and conformational flexibility.
- Reported high purity suitable for research and synthesis workflows.
- Available in research-scale quantities for method development.
eMolecules 635287-26-2 | Fmoc-NH-PEG5-CH2COOH | MFCD26142982 | 1g
Ambeed | Fmoc-NH-PEG5-CH2COOH | 1g | 506391038 | A474989 | 635287-26-2 | MFCD26142982 | 517.575 | C27H35NO9
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Medchemexpress LLC Propargyl-PEG6-N3 | 1198080-03-3 | 100 MG
Propargyl-PEG6-N3 is a PEG-based PROTAC linker employed in the synthesis of PROTACs. It functions as a versatile click chemistry reagent, featuring an Azide group. This group readily participates in copper-catalyzed azide-alkyne cycloaddition reactions (CuAAc) when combined with molecules containing Alkyne groups. Furthermore, it can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules that possess DBCO or BCN groups, offering flexible synthetic pathways.
- PEG-based PROTAC linker.
- Used in the synthesis of PROTACs.
- Click chemistry reagent.
- Contains an Azide group.
- Participates in copper-catalyzed azide-alkyne cycloaddition reactions (CuAAc) with Alkyne groups.
- Undergoes strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN groups.
Medchemexpress LLC Dspe-peg-amine (ammonium) | 474922-26-4 | 98.8% | 1000 (average) | (C2H4O)nN2O10P·NH3 | 25 MG
DSPE-PEG-Amine (average MW 1000, ammonium salt) is a PEGylated phospholipid with a terminal primary amine used to functionalize liposomes and nanoparticles. The hydrophobic DSPE anchor incorporates into lipid bilayers while the PEG spacer presents a reactive amine at the particle surface for covalent conjugation to ligands, dyes, or biomolecules in delivery and surface-modification applications.
- PEGylated phospholipid with terminal primary amine.
- Average molecular weight approximately 1000 daltons.
- Ammonium salt form to aid handling and solubility.
- Enables covalent conjugation to NHS-esters, aldehydes, and other activated groups.
- Integrates into liposome bilayers for surface functionalization.
- Suitable for nanoparticle coating and targeted delivery research.
Cayman Chemical AdenosIn amIn congenr 10mg
An adenosine A1 receptor agonist; selectively binds adenosine A1 over A2A and A3 receptors (Kis = 0.85, 210, and 281 nM, respectively, for the rat receptors); increases survival and prevents neuronal damage in the hippocampal CA1 region in a gerbil model of bilateral carotid artery occlusion-induced cerebral ischemia at 75 UG/kg; protects against auditory threshold shifits and inner and outer hair cell loss in rats following noise exposure at 110 dB at 100 UG/kg
![Alkali Scientific PEG 8000 [Polyethylene Glycol 8000], 25 Kg](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000661610.jpg-250.jpg)
Alkali Scientific PEG 8000 [Polyethylene Glycol 8000], 25 Kg
Polyethylene Glycol 8000 (PEG 8000) is a high-molecular-weight polymer with a wide range of applications in molecular biology and biochemistry. This reagent, with a molecular weight of 8000, is primarily used for inducing molecular crowding, which helps study protein interactions and enhance enzyme stability. It is commonly used for protein precipitation, solubilizing membrane proteins, and in DNA extraction procedures. PEG 8000 is also crucial for macromolecular studies, such as DNA-protein interactions, and is often used in crystallography. Available in a 25 kg package, this product is designed to support large-scale research needs and repetitive experimental protocols.
Medchemexpress LLC HY-103602A 100mg Medchemexpress, (S,R,S)-AHPC-PEG3-NH2 CAS:2010159-56-3 Purity:>98%
Medchemexpress, HY-103602A 100mg (S,R,S)-AHPC-PEG3-NH2 CAS:2010159-56-3 (S,R,S)-AHPC-PEG3-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and 3-unit PEG linker used in PROTAC technology. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
eMolecules 1263044-40-1 | Medchem Express | Biotin-PEG3-OH | 50mg | 781212818 | HY-135924 | 375.48 | C16H29N3O5S
AstaTech | 28-DICHLOROQUINOLINE-3-CARBOXALDEHYDE | 1g | 200610555 | 52861 | 97.000 | 144918-96-7 | MFCD06202349 | 226.060 | C10H5Cl2NO
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Medchemexpress LLC m-PEG15-amine | 2745717-94-4 | 99.9% | 691.85 | 25 MG
m-PEG15-amine (CAS No.: 2745717-94-4) is a high-purity PEG-based PROTAC linker with a molecular formula of C31H65NO15 and a molecular weight of 691.85.
- High purity of 99.9%
- Appears as a colorless to light yellow oil
- Store at -20°C under nitrogen
- When in solvent, store at -80°C for 6 months or -20°C for 1 month under nitrogen